AMM 338: Botox Resistance Decoded: Unraveling Myths and Realities
January 27, 2025
This episode delves into the evolving issue of botox resistance in aesthetic medicine. Michelle Grant, a dermatology clinic manager, shares her personal experience of reduced efficacy from routine botox injections. Dermatologist Dr. Corey L. Hartman and cosmetic surgeon Robert M. Schwarcz discuss the complexities of diagnosing botox resistance, which is a rare occurrence where antibodies render botox less effective. The episode explores possible contributing factors, including dosage, injection technique, and unproven links to the COVID-19 Pfizer vaccine. Listeners will gain insights into the limited research available, the importance of consulting specialists, and potential solutions for those experiencing reduced results from botox treatments.
Quick Takes
- Botox resistance is a rare occurrence where antibodies render botox less effective.
- Diagnosing resistance typically requires blood tests and may be attributed to factors like dosage or improper placement.
- Some suggest a potential link between botox resistance and the COVID-19 vaccine, particularly Pfizer, but evidence remains inconclusive.
Episode Transcript
Today is January 27, 2025. There’s an evolving conversation about botox resistance in the aesthetic medicine world. This rare occurrence happens when someone develops antibodies that render botox less effective. Michelle Grant, a manager at a dermatology clinic in Birmingham, Alabama, shares her experience, noting that her routine injections have lost their punch.
Dermatologist Dr. Corey L. Hartman explains that diagnosing this resistance is challenging and typically requires blood tests. He’s encountered a few patients with this issue, where the botox effects fail to last as expected. Despite the rarity, other factors like dosage, improper placement, or even the type of toxin used might explain the perceived resistance.
Cosmetic surgeon Robert M. Schwarcz adds that resistance arises when the body blocks the neurotoxin, preventing muscle paralysis. Yet, pinpointing the exact cause is tricky. Interestingly, some suggest a potential link between botox resistance and the COVID-19 vaccine, notably Pfizer, although evidence remains inconclusive.
A study published in the Journal of Cosmetic Dermatology hints at botox A’s reduced efficacy post-vaccination, but this involved a limited number of cases. Dr. Schwarcz notes he’s not observed such a connection in numerous vaccinated patients. For now, resistance remains elusive, with solutions often found in modifying dosage or injection techniques. Always consult a specialist to explore the best options. Have an excellent day!