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AMM 192: Unlocking Radiance: Secrets of Modern Dermal Fillers

September 05, 2024

In this episode, we explore the evolution of dermal fillers throughout the early 21st century, focusing on the shift from simple fine line corrections to enhancing soft tissue volume and bone contour. The discussion highlights the innovative technique of “filler blending,” where practitioners mix fillers to alter their physical properties. A recent survey indicates the growing popularity of hyperdilute calcium hydroxylapatite-carboxymethylcellulose implant gels in bioregenerative applications. The episode also delves into the concept of titrated hypodilution of these gels to adjust their properties for tailored treatments, emphasizing the future of personalized approaches in aesthetic medicine.

Quick Takes

  • Transition from addressing fine lines to enhancing soft tissue volume and bone contour
  • Advancement of “filler blending” by mixing fillers to alter physical properties
  • New concept of titrated hypodilution of CaHA-CMC to tailor filler’s properties for different needs

Episode Transcript

Today is September 5th and we’re diving into the fascinating evolution of dermal fillers over the early 21st century. We’ve transitioned from merely addressing fine lines to enhancing soft tissue volume and even bone contour. This evolution has been driven by the rising use of innovative bioregenerative applications and a heightened awareness of use-specific fillers.

One notable advancement is “filler blending,” where practitioners mix fillers to alter their physical properties. A recent survey of nearly 500 dermatologists shows this technique is gaining traction. Hyperdilute calcium hydroxylapatite-carboxymethylcellulose (CaHA-CMC) implant gels, like Radiesse from Merz Aesthetics, have shown promising results in bioregenerative applications. This includes improvements in skin quality and elasticity.

However, the study brings forward a new concept: titrated hypodilution of CaHA-CMC. Essentially, this means mixing the filler with saline at less than a 1:1 ratio to customize its properties. The findings suggest that by adjusting the dilution, we can tailor the filler’s elasticity and cohesiveness to match different needs—ranging from direct tissue filling to more fluid-like biostimulatory effects.

As we continue to explore these advancements, it’s clear that the ability to customize dermal fillers will play a crucial role in aesthetic medicine, ensuring more personalized and effective treatments for patients.

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Aesthetic Medicine Minute

with Dr. Teri Fisher

Daily insights, updates, and strategies for navigating the world of medical aesthetics, all in 1 minute per day.